Science & Tech

What is the Garbh-Ini Programme?

The Garbh-Ini program’s scientists discovered 19 single nucleotide polymorphisms (SNPs) or genetic markers linked to preterm or premature delivery.

What exactly is Garbh-Ini?

  • It is an interdisciplinary research programme in India that focuses on advanced birth outcomes research.
  • It is a joint endeavour of the Department of Biotechnology.
  • It is led by the DBT-Translational Health Science and Technology Institute (THSTI) at Faridabad’s NCR Biotech cluster, in partnership with the DBT-NIBMG, Kalyani, the DBT-Regional Centre for Biotechnology (RCB), Gurugram Civil Hospital, and other organisations.
  • The program’s goal is to use modern technologies to improve mother and child health outcomes and address India’s high rate of preterm deliveries.

SNPs are Single Nucleotide Polymorphisms

  • Genetic markers are DNA sequences that can be used to identify an individual or a certain trait.
  • SNPs (single nucleotide polymorphisms) are the most common sort of genetic variation seen in DNA sequences.
  • When a single nucleotide (A, C, T, or G) in the DNA sequence changes, an SNP occurs.
  • These alterations can occur in any area of the genome and can be used to identify certain features or disease vulnerability as genetic markers.

The Importance of the Research

  • The study is significant since it discovers 19 SNPs or genetic markers linked to preterm or premature delivery.
  • Five of the 19 SNPs were linked to an elevated risk of early preterm delivery (born before 33 weeks) and can be used to predict premature births.
  • This is the first South Asian study to find genetic markers linked to preterm births, and it has important implications for improving maternal and child health outcomes in India.
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